The “supply chain” refers to the structure formed by the actors involved in the entire process from the production of chemical substances or mixtures to their delivery to the end user, namely manufacturers, importers, downstream users and distributors. In this process, each actor in the supply chain is responsible for sharing information about chemicals, communicating safety data sheets and ensuring the safe use of chemicals. This flow of information in the supply chain is important for the safe use of chemicals and the protection of human health and the environment.